An excerpt from the article “Mystery and Evidence,” by Tim Crane.

“Religious belief tolerates a high degree of mystery and ignorance in its understanding of the world. When the devout pray, and their prayers are not answered, they do not take this as evidence which has to be weighed alongside all the other evidence that prayer is effective. They feel no obligation whatsoever to weigh the evidence. If God does not answer their prayers, well, there must be some explanation of this, even though we may never know it. Why do people suffer if an omnipotent God loves them? Many complex answers have been offered, but in the end they come down to this: it’s a mystery.

Science too has its share of mysteries (or rather: things that must simply be accepted without further explanation). But one aim of science is to minimize such things, to reduce the number of primitive concepts or primitive explanations. The religious attitude is very different. It does not seek to minimize mystery. Mysteries are accepted as a consequence of what, for the religious, makes the world meaningful.

This point gets to the heart of the difference between science and religion. Religion is an attempt to make sense of the world, but it does not try and do this in the way science does. Science makes sense of the world by showing how things conform to its hypotheses. The characteristic mode of scientific explanation is showing how events fit into a general pattern.”